Pages

Tuesday, January 31, 2017

Android Generate QR code using ZXing library

Android Generate QR code using ZXing library



Available link for download

Read more »

Angry Birds Transformers v1 14 3 Mods

Angry Birds Transformers v1 14 3 Mods


Angry Birds Transformers v1.14.3 [Mods]
Angry Birds Transformers v1.14.3 [Mods]
Requirements: Android 4.0+

Angry Birds and Transformers collide in this action-packed, 3D shoot ‘em up adventure!
The EggSpark has transformed the eggs into crazed robots who are destroying Piggy Island, but who can stop them?! Autobirds, ROLL OUT!
Have you ever seen an alien robot Angry Bird? Enter the AUTOBIRDS! This brave band of heroes features Red as Optimus Prime, Chuck as Bumblebee and… well you’ll meet the rest soon. They’ve got lasers and they turn into cars. Plus they have arms and legs – that’s a first!
But the courageous Autobirds can’t save Piggy Island on their own – to stop the EggBots they’ll need to join forces with their arch rivals the DECEPTIHOGS (like Decepticons only smellier). Can these bitter enemies team up and put aside their differences? Yeah right...
- COLLECT! Unlock a roster of heroes (and villains) with unique attacks and abilities!
- DESTROY! Leave the slingshot at home – this time you have some SERIOUS firepower!
- VEHICLES! Oh, yes! Car, truck, tank or plane – transform to dodge falling hazards!
- UPGRADES! Get stronger weapons and new abilities for every Transformer!
- TAG TEAM! Borrow a friend’s character to unleash a devastating two-bot assault!
- TELEPODS™! Scan ‘em to unlock, revive or boost your bots!
*NOTE:
A network connection is required for some game features.
WHATS NEW
**INCOMING TRANSMISSION FROM TELETRAAN 1**
/BOUNTY HUNT! Join in with the new competition event and pop some pigs!
/HEAVY ATTACK! Win accessories for Lockdown and his variants!
/OPTIMISED EXPERIENCE! We continue to improve the game and crush bugs!
 
Mod 1:
1. Infinite Coins After Increased
2. Jenga Unlocked

Mod 2:
1. Infinite Coins After Increased
2. Jenga Unlocked
3. No Damage
 
 
More Info:
https://play.google.com/store/apps/d...dstransformers
 
Download Instructions:
Mod 1:
https://userscloud.com/e83cf7zsw4n3
http://ul.to/de0zrh6a
https://dailyuploads.net/jz6qkinif0hv
Mod 2:
https://userscloud.com/0kmdkququu9b
http://ul.to/1mrbysow
https://dailyuploads.net/31jl4xfuy1yg
OBB:

https://userscloud.com/31bxhuj2zsqm
http://ul.to/4x786rdx
https://dailyuploads.net/g521aqg825fo

Available link for download

Read more »

Anika amazed to see Shivaays lover boy side in Ishqbaaz

Anika amazed to see Shivaays lover boy side in Ishqbaaz




In Star Plus Show Ishqbaaz   Tia (Navina Bole)  irked eyeing Shivaays efforts for Anika (Surbhi Chandna)

The upcoming chapter of Ishqbaaz will show some lighter moments amid Shivaay and Anika.

Shivaay is slready tensed over Swetlanas accidebt news and after knowing thst someone was breaching housw security.

Shivaay just want his famiky to stay safe at any cost and thus is  tensed while Anika calms him down.

Shivaay and Anika has started to come closer to each other and knows how one another is feeling.

Shivaay makes attempts to make Anika feel soecial and thus decides to mske breakfast for her.

Shivaay impresses Anika

Anika is shocked seeing Shivaays lover boy side which she has never veen through and appreciates it.

Shivaay makes Anikas favourite aloo puri for her to make her happy,  Shivaay and Anika shares romantic eyelock moments.

Keep Reading For MoreUpdates Of Star Plus Ishqbaaz

Available link for download

Read more »

Anatomy of Lehmans Failure and the Importance of Liquidity Requirements

Anatomy of Lehmans Failure and the Importance of Liquidity Requirements


Remember the Lehman Examiners Report? The 4000+ page report by the court-appointed examiner was lauded for a couple of weeks after it was released, and then largely forgotten. The media and blogosphere quickly moved on to the next outrage-du-jour (among others, the SECs suit against Goldman), and never looked back. Well, I did not forget about it, and thanks to the uptick in flights — and thus reading time — in the last few months, I can now credibly claim to have read....well, not every single word in the Examiners Report (some appendices are just pages of CUSIPs), but all of the substantive sections, including all of the substantive appendices, and many of the underlying documents.

First of all, let me just say that Anton Valukas and the lawyers at Jenner & Block who wrote the Examiners Report did a masterful job. I was, and continue to be, in awe of the quality and comprehensiveness of the report. The fact that they were able to do all the research, conduct all the interviews, and write the 4,000+ page report in a little over one year is amazing, and makes me incredibly jealous of their productivity.

Now, since I read the whole damn thing, I think I have a pretty good handle on what went wrong at Lehman, and why it failed. Obviously, there isnt just one reason why Lehman failed, despite what most commentators would have you believe. But theres one issue that stands out to me as the biggest problem at Lehman — in short, they were misrepresenting their liquidity pool. In a huge way.

Its disappointing that this issue has been almost completely overlooked, because the brazenness of their misrepresentation was shocking. I think the best way to think about it is this: on Friday, September 12, Lehman claimed that it had a $32.5bn liquidity pool, and on Monday, September 15, Lehman needed $16bn to finance non-central bank eligible collateral. So why, if their liquidity pool was twice the size of their funding requirement, did they have to file for bankruptcy? The answer is that Lehman didnt actually have a $32.5bn liquidity pool; they had, at most, a $2.5bn liquidity pool. That is not a typo.

Earlier in 2008, Lehmans two main clearing banks, JPMorgan and Citi, started requiring Lehman to collateralize its intraday exposures. (Previously, the clearing banks would repay Lehmans tri-party repo lenders at the beginning of the day, and wouldnt require Lehman to pay back this advance until the end of the day.) Lehman reluctantly agreed, but requested that the banks release the collateral at the end of each day. Why did they care if the banks released the collateral every night if it just had to be posted again the next morning? Because Lehman calculated its reportable liquidity at the end of each day, and if the clearing-bank collateral was released at the end of each day, Lehman considered it part of the "liquidity pool." By the end, roughly $19bn of the $32.5bn liquidity pool consisted of clearing-bank collateral.

In no functional sense was the clearing-bank collateral "unencumbered" — if Lehman requested the collateral back, JPMorgan and Citi would have at the very least required them to pre-fund their trades (which Lehman didnt have the cash to do), and more likely would have just stopped clearing their trades. People at Lehman admitted as much to the Examiner. And once a broker-dealers clearing bank stops clearing its trades, the broker-dealer is finished. Including the clearing-bank collateral in its liquidity pool was not only inappropriate, but also aggressively deceptive.

But wait, theres more. Lehman was also including in its liquidity pool non-central bank eligible CLOs and CDOs. And they had the audacity to mark these CLOs and CDOs at 100 (par) for purposes of the liquidity pool, even though JPMorgans third-party pricing vendor marked them at 50–60.

Unfortunately, I cant do much in the way of legal analysis of the propriety of Lehmans decision to include clearing-bank collateral and junk CLOs/CDOs in its liquidity pool, because as the Examiner rightly points out, "No law, SEC regulation or GAAP-style rule governed the definition of a liquid asset in the context of a CSE’s liquidity pool." The SEC considered an asset to be "liquid" if it could be monetized in less than 24 hours (though the SEC never enforced this definition, or wrote it into an actual rule). The "24 hours" standard is, in my opinion, the consensus in the industry — that is, I think if you asked most market participants, they would agree that at least most of the assets in a reportable "liquidity pool" should be able to be monetized in 24 hours.

Lehmans Global Treasurer, Paolo Tonucci (who really comes off as a Bad Guy in this episode), claimed that "Lehmans internal definition of a liquid asset, appropriate for inclusion in the liquidity pool, was one that could be monetized within five days." (Examiners Report, pg. 1412) Tellingly, in a footnote, the Examiner notes that "Tonucci could not cite a particular Lehman document that established this five-day definition." Lehmans International Treasurer, Carlos Pellerani, said he had never heard of this alleged "five-day" standard. (Examiners Report, Appendix 20, pg. 10)

Of course, even by this "five-day" standard, Lehman was still misrepresenting its liquidity pool. Lehman broke down its liquidity pool into "ability to monetize" categories: assets with a "high" ability to monetize could be liquidated in one day, assets assigned a "mid" rating could be liquidated within five days, and assets assigned a "low" rating could be monetized within one to two weeks. (Examiners Report, Appendix 20, pg. 10) By September 12, $30bn of Lehmans $32.5bn liquidity pool had a "low" ability to monetize:


This is a freaking liquidity pool, and youre telling me that 92% of it can only be monetized in a week or two? Unreal. By contrast, heres how Goldman defines its liquidity pool in its 10-Qs (emphasis added):
The U.S. dollar-denominated [Global Core] Excess [i.e., liquidity pool] is comprised of only unencumbered U.S. government securities, U.S. agency securities and highly liquid U.S. agency mortgage-backed securities, all of which are eligible as collateral in Federal Reserve open market operations, as well as certain overnight cash deposits. Our non-U.S. dollar-denominated excess is comprised of only unencumbered French, German, United Kingdom and Japanese government bonds and certain overnight cash deposits in highly liquid currencies. We strictly limit our Global Core Excess to this narrowly defined list of securities and cash because we believe they are highly liquid, even in a difficult funding environment. We do not believe that other potential sources of excess liquidity, such as lower-quality unencumbered securities or committed credit facilities, are as reliable in a liquidity crisis.
Using this definition (which is standard), Lehman had a liquidity pool of maybe $1.9bn on Friday, September 12.

Now, Lehman wasnt always misrepresenting its liquidity pool. By the end of May, at least, it had a legitimate liquidity pool of over $40bn. But over the Summer of 2008, its liquidity pool steadily deteriorated, and Lehman simply refused to recognize this deterioration in its reported liquidity. JPMorgan and Citi demanded around $14bn more in collateral, and large asset managers — most importantly, Fidelity — pulled Lehmans repo lines and stopped rolling their paper. As of June 30, 2008, Fidelity had $14.1bn of repo lines in place with Lehman; by Thursday, September 11, Fidelity had pulled the entire $14.1bn balance.

As you can see from the chart above, Tuesday, September 9th was the real Day of Days for Lehman in terms of funding. On Monday night, news broke that Korea Development Bank had decided not to invest in Lehman. On Tuesday, repo counterparties pulled roughly $14bn of funding. Heres the breakdown of counterparties who pulled repo lines that day:



Notice that these are all large institutional asset managers — PIMCO, Morgan Stanley, Barclays, etc. — rather than those supposedly skittish retail investors. This was, essentially, the end for Lehman. There was no way they could replace $14bn of secured funding that quickly, especially after reporting such terrible earnings the next day.

All of this highlights the importance of establishing liquidity requirements with a clear definition of a "liquid" asset — which, fortunately, is something Basel III does, and does rather conservatively. Ill save that for another post, though.

Available link for download

Read more »

Angry Birds 2 Hack Tool

Angry Birds 2 Hack Tool


Angry Birds 2 Hack Tool
Today well present the newest hack we made, which we know well be a hit, like all the others hacks from us: Angry Birds 2 Hack Tool. Yes, yes! The Angry Birds are returning in a new game!
But if you are a true fan, you probably know this already...So, basically, this is the, we-dont-even-know which title of the franchise. What we know is that this isnt the first hack we make for a game with those birds. We have already made a hack for Angry Birds Stella.
Returning to the hack from this article, we have to say some words about it: it is the best Angry Birds 2 Hack Tool! Yeah, Yeah, you hear that a lot, but we wont say anything else. Well let you download it from below and see it by yourself.
The whole process is simple. You have to read this article entirely. Why? Because you have to know what you will download and also, how to use it.  Then, you have to go below and select a Download button to get your hack tool. Then, you have to install it. Then, you have to open it and be amazed by it:
Angry Birds 2 Hack Tool
As you see, it it easy to use. It has a friendly-user interface and everybody will be able to use it at its full potential. We know those birds have fans from kindergardeners to adults and we thought the simplicity will be a strong point in buolding this Angry Birds 2 Hack Tool.
You will have to connect your device to the hack tool. Heres a thing we have to tell you, a thing which somewhere else would be a problem for you, but not here. Sometimes, the hacks you find dont work on your device, because their creators dont want to work more in making it available to every platform. But the team behind this Angry Birds 2 Hack Tool isnt lazy and thats why it isnt important what device you use. Because, the software will work perfectly fine with every type of device.
Using the hack we provide, you will become the best player amoung your friends. They will see you are getting better and better, but they wont know how you are doing it! You will be able to get unlimited gems fast and easy! And with those gems, you will have everything you want in-game. Isnt Angry Birds 2 Hack Tool great?
Press "Start" and sit back, watching how the hack will do its job. By the way, you will not have to search periodically for updates of the software. We thought it would be horrible and thats why we implemented the "Auto-Update" function, which will be nice, because the Angry Birds 2 Hack Tool will renew itself everytime a new update is available.
So, you will  have everything you need to be the best, you will have unlimited gems fast and easy and everything will happen if you download right now the Angry Birds 2 Hack Tool we provide from below. Are you ready?
mana-download
fdgdgfdgdfg
button2
button3

Available link for download

Read more »

App Cache Cleaner Pro Clean 5 0

App Cache Cleaner Pro Clean 5 0


App Cache Cleaner Pro - Clean 5.0 APK Free Download Android App. Best Cache Cleaner! App Cache Cleaner,a quick tool for clearing application cached files. One Tap to clean all cached files for getting more avalable space. This tool can free a lot of storage memory for your phone. Free phone internal momeory, Get more internal rom storage.





Instructions :

  • Download App
  • Install APK


It is an app which is crucial to anyone who has memory management issues. If you running out of application storage, you now can get more available storage space by clearing apps created cache/data files.
You dont have to ROOT the phone anymore!

Features:

  • 1-tap to clear all cached files
  • auto clear when you open this app
  • auto clear all cache at a specified interval
  • auto exit when you cleaned all cached files
  • clear cache for a specified application
  • list applications by either cache size or app name

By long pressing any item in the app list, you can:
Share apps with your friends

  • view application on Market
  • uninstall applications which has cached files
  • open application
  • show application details page

If you just want to clear all cached files, you dont need to wait the completion of building apps list, just tap the Clear All Cache Files button.

Whats in this version : (Updated : Dec 17, 2013)

  • improved UI

Required Android O/S : 1.6+

Screenshots :




Download App Cache Cleaner Pro - Clean 5.0 APK

Download App Cache Cleaner Pro - Clean 5.0 Free Apk
Download App Cache Cleaner Pro - Clean 5.0 Google Play Store


Available link for download

Read more »

Ants

Ants




Juste des idees, il faut travailler davantage la courbe pour lanimation.

Available link for download

Read more »

Amnesty International responds to AG James Caldwell Louisianas justice keeps man locked up in isolation for over 40 years

Amnesty International responds to AG James Caldwell Louisianas justice keeps man locked up in isolation for over 40 years


Reprinted below is a statement from Amnesty International, made in response to an email released last week by Louisiana Attorney General James Caldwell, where among other things, he claimed that the Angola 3 "have never been in solitary confinement." Please support Amnestys campaign urging Caldwell to not appeal last months ruling that overturned Albert Woodfoxs conviction for a third time. Take action here!


Louisiana’s “justice” keeps man locked up in isolation for over 40 years

By Amnesty International

March 26, 2013

Albert Woodfox has spent more than half his life in a cell just three paces wide and four paces long.

The 66-year-old man was convicted in 1972 of the murder of Brent Miller, a prison guard.

He claims he is innocent and organizations including Amnesty International have said his case raises serious legal and human rights concerns.

A federal district court in Louisiana recently ruled that his conviction should be overturned.

But Louisiana Attorney General James Caldwell has said he will appeal the ruling.

He says Albert Woodfox is a “career criminal” who should remain behind bars.

The case continues to paint a disturbing picture of justice in Louisiana.

In 2008, the same federal district court issued a ruling that overturned Albert Woodfox’s conviction though he remained in prison pending the bail hearing.

During this time, the Attorney General’s office emailed the neighbours of Woodfox’s niece, to whom he was intended to be released on bail, to advise them that that her uncle was a violent rapist and convicted murderer. He urged the neighbours to sign petitions to oppose his release.

When the federal district court subsequently ordered that Woodfox be released on bail, the judge criticized the Attorney General’s intimidation campaign.

Despite the bail order, Woodfox remained in prison following another intervention by the Attorney General who appealed this recommendation to a higher court.

Attorney General Caldwell has recently renewed his public attacks, circulating allegations about Woodfoxs alleged criminal activities in the 1960s, linking him to unsolved rapes and sexual assaults, and insisting that the states murder case against Woodfox is "very strong".

Setting the record straight

Albert Woodfox has never been tried or convicted of rape. Nor, after 41 years in prison, does his disciplinary record indicate that he is dangerous or violent. The prison system’s own mental health assessments indicate that he does not pose a threat to himself or others.

He has been tried twice for the murder of Brent Miller. The first conviction was overturned and he was retried and reconvicted. That conviction was overturned and then reinstated on appeal. Now this latest ruling overturns the conviction again.

At the original trial, the conviction relied heavily on testimony from Hezekiah Brown – who was the only witness to testify to actually seeing Albert commit the murder - as well as statements from four other fellow inmates.

There was no physical evidence linking Albert Woodfox to the murder. DNA evidence that was potentially favourable to the defendant has been lost - a bloody fingerprint found close to the body didn’t match any of the four defendants, and no attempt has been made by the State or prison officials to identify it through the prison fingerprint database.

Evidence has emerged since Hezekiah Brown’s death in 1996 that in return for his testimony, he had received benefits from the state – including immediate transfer from the prison to a cottage on the grounds and a weekly ration of a carton of cigarettes.

For more than 10 years, the Warden petitioned repeatedly for a pardon for Brown, which was finally granted in 1986.

According to a magistrate judge who reviewed the case in 2008, Brown’s testimony was “so critical to [the prosecution’s] case that without it there would probably be no case.”

Two of the four eyewitnesses who testified to Albert Woodfox’s involvement in the crime have since recanted their testimony. One has stated that he made up his testimony because he had been told by officials that they would help him transfer out of Angola prison.

Colonel Nyati Bast, a former inmate, testified during Albert Woodfox’s first trial that he was with him in the dining hall at the time of the attack on Brent Miller, which took place in another part of the prison.

Bast was placed in solitary confinement soon after he revealed this information to prison officials, and remained there for the duration of his 20-year sentence. He stands by his original testimony.

Of the remaining witnesses, one was legally blind and the other was heavily medicated at the time of the murder.

Real justice

The inconsistencies and flaws in the legal process led Brent Miller’s widow in 2008 to call for a new investigation into the case: “If they did not do this – and I believe they didn’t – they have been living a nightmare for 36 years”.

Albert Woodfox has been kept in solitary confinement for more than 40 years – held for 23 hours a day in a small, starkly furnished cell, and allowed out only to walk along the cell corridor, shower or exercise alone.

He has been deprived of access to work, rehabilitative programmes and group activity. As a consequence of these conditions, his physical and mental health has deteriorated.

Amnesty International is appealing to the Attorney General not to appeal the District Court’s recent ruling.

“Enough is enough. After four decades, real justice in this case is long overdue.” said Tessa Murphy, USA Campaigner at Amnesty International. “The ruling by the federal district court should be allowed to stand.”

Available link for download

Read more »

Monday, January 30, 2017

Akh Boldi आँख बोल्दी Karn Sekhon Full Lyrics Full Video Song Hd Mp4

Akh Boldi आँख बोल्दी Karn Sekhon Full Lyrics Full Video Song Hd Mp4


Akh Boldi - ??? ?????? (Karn Sekhon) Full Lyrics Video Song Hd
Akh Boldi - ??? ??????  (Karn Sekhon) Full Lyrics Video Song Hd 


Song: Akh Boldi
Singer: Karn Sekhon

Lyrics: Desi Crew

Music: Veerpal Thind


Lyrics Of Akh Boldi In Hindi:


Lakh Te Hazar Na Crore Dewange
Ni Mull Tere Nakhre Da Mod Dewange

Supne Ne Tere Jo Kaware Allahde
Sadde Aan Khwaaban De Naal Thair Taan Sahi


Jehdi Gall Jeede Teri Akh Boldi

Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 
Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 


Turda Shaukeen Siga Hik Kad Ke

Ni Nakhre Tere Nu Sut Ditta Chab Ke

Ni Nakhre Tere Nu Sut Ditta Chab Ke


Ho Vekhi Jatt Laggiyan De Mull Mod Doon
Ho Mull Sadde Pehran Wale Pain Taan Sahi


Jehdi Gall Jeede Teri Akh Boldi
Ho Buliyan Nu Aakh Kade Kehn Taan Sahi


Jattan De Mundey Di Addi Pind Janda

Jana Khana Billo Saddi Hind Janda

Jana Khana Billo Saddi Hind Janda


Aukhi Hundi Apni Jo Mang Chhadni
Hor Koyi Aave Laawa Lain Taan Sahi


Jehdi Gall Jeede Teri Akh Boldi

Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 
Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 

Chadhdi Jawani Meri Badi Tatti Ae

Payengi Punware Ni Billori Akhiye 

Payengi Punware Ni Billori Akhiye 


Jehde Tainu Rok De Ne Meri Hon Ton
Ho Sikh Naal Pange Kade Lain Taan Sahi


Jehdi Gall Jeede Teri Akh Boldi

Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 

Ho Buliyan Nu Aakh Kade Kehn Taan Sahi 



Akh Boldi Full Song Official Video Youtube:






Available link for download

Read more »

Another Award from 3D Total !

Another Award from 3D Total !



thanks again to 3 D total for their award of excellence. ive made a step by step tutorial for the Steampunk Village and am working on one for this image as well. ill let you know when its available and posted on their site!

Available link for download

Read more »

Amaia for Franke

Amaia for Franke


Dia 1
Basel: Básicamente, llueve y hace frío. 
Creo que me he mediterraneizado, a veces me olvido que vengo de Invernalia. 
Pack de regalo que Franke regala con mis ilustraciones. 
El mural se divide en 5 partes, cada día hago una parte.
Mención especial a mi assistant. Sin él no lo podría estar haciendo.

Dia 2
Party Vip para todo el equipo. A las 7 aquí ya es de noche y cuando me bajé del tranvía... zas! en el hall del Swiss Bau, como si fuera mi propio Times Square...
Y dentro...pues la fiesta del queso.
Cualquiera diría que estamos en Suiza.
Atención al queso de en medio...
 Día 3
Boceto versus mural.  
Mañana más.

Si quieres saber más cosas sobre mí y mi vida, sígueme en Instagram, Twitter o Facebook.

Available link for download

Read more »

Another Breakfast Bloggie

Another Breakfast Bloggie


The 2008 Bloggies are go. Vote early. Vote often. Actually, you can only vote once. Choose wisely, grasshoppers...

bloggies 2008

Available link for download

Read more »

ALS Part 2

ALS Part 2



There are no direct known causes yet of ALS. However, a number of genetic mutations have been associated with various types of ALS.


Defect on chromosome 21

A defect on chromosome 21, which codes for superoxide dismutase, is associated with approximately 20% of familial cases of ALS, or about 2% of ALS cases overall. This mutation is believed to be transmitted in an autosomal dominant manner, and has over a hundred different forms of mutation. 


Hexanucleotide

In 2011, a genetic abnormality known as a hexanucleotide repeat was found, which is associated with ALS combined with frontotemporal dementia and accounts for some 6% of cases of ALS. 


BCAA

Certain studies suggested a link between sporadic ALS, specifically in athletes, and a diet enriched with branched-chain amino acids. BCAAs, a common dietary supplement among athletes, cause cell hyper-excitability resembling that usually observed in ALS patients. The proposed underlying mechanism is that cell hyper-excitability results in increased calcium absorption by the cell and thus brings about cell death of neuronal cells, which have particularly low calcium buffering capabilities.


Lesion to the motor system

Another very common cause of ALS is a lesion to the motor system in areas such as the frontotemporal lobes. Lesions in these areas often show signs of early deficit, which can be used to predict the loss of motor function, and result in the spread of ALS.


Many other potential causes, including chemical exposure, electromagnetic field exposure, occupation, physical trauma, and electric shock, have been investigated but without consistent findings.


There is still no known cure for ALS. But there are treatments. There is Rilutek, which slows down the progression of the disease. Other nutrients that show promise are: creatine, CoQ10, Vitamin D, Vitamin E, alpha lipoid acid and lithium, which has been said to show the most successful demonstration as treatment to ALS.

But naturally, keeping oneself healthy and the immune system strong can help combat any disease.






Available link for download

Read more »

Another Wednesday

Another Wednesday


I am exhausted. This week I am in a temping job which is sucking my soul out with a blunt syringe. I have tried a few things to cope. I have tried ignoring it, hoping it will go away. I have tried thinking happy thoughts. I have tried cheese twists (with mustard on them). Nothing works, and I fear that my options are diminishing rapidly.

(I am watching Top Gear. I find Richard Hammond curiously alluring and the cars shiny but inexplicable.)

I have a gig on Monday, as a result of the other gig we did a few weeks ago in Kilburn. My head has been whirling all day with songs, but now Im home all I can seem to have the energy to do is sit, blog, ignore the television and be elbowed by the dog.

(I am at my parents house, even though I now have a home of my own in Brixton. It lies empty. I have to wait until the weekend to get any of my stuff there. I still dont have a bed.)

(Jeremy Clarkson is being witty but irritating. My big sister will be round in a bit. My Mum is cooking nice things with prawns in. The dog appears to be licking a sofa cushion.)

I have nothing to write except for disparate nothings. Temping is horrible and it makes me cross and really rather void of personality.

The phone is ringing, and I have to go and do something to negate the hours I have spent staring hopelessly at spreadsheets today. Spreadsheets are not my friends.

A glass of red wine sits waiting for me so I will drink it and spur myself to do something productive. Hang on, let me find some enthusiasm.

Now I have found some! My sister is here! I will put the depression of temping and the pressure of lost productivity behind me, set the table and go and relax.

UPDATE:

It is just after six thirty in the morning. I am staring down the barrel of another whole day in a job the very thought of which makes me want to throw up. I cant decide what to wear because I dont own much suitable for the firey pits of hell (smart casual).

Last night I could barely even talk from horror at the thought of having to get up this morning. I made a phonecall, hung up after a meagre five minutes because I had nothing to say that wouldnt have just sounded like a series of high-pitched wails about my pathetic excuse for a life. I dont want to inflict that on my friends so instead I must turn to the Internet.

This job, it would appear, has brought out the drama queen in me. Never very far from the surface anyway, she has emerged in full regalia, bursting with anguish.

Today I will try to refuse to be paralysed by this, try to use every spare minute to plan and make changes. It is difficult, though, because I feel for all the world like a train just hit me.

Available link for download

Read more »

AlphaBetty Saga 1 0 5 APK

AlphaBetty Saga 1 0 5 APK


King, the developer behind a successful of Candy Crush Saga and Farm Heroes Saga has released its new Puzzle game called AlphaBetty Saga for Android player. With that in mind, it has finally hit App Store and Google Play. As always, you can download directly the APK file of this game here. Skip to the bottom of this article for a direct link to the new AlphaBetty APK.

AlphaBetty Saga APK

AlphaBetty Saga is a brand new, free word game that will take players on a rip-roaring adventure to the far-flung corners of the mouse world. Players task to join Professor Alpha, Betty and their loyal friend Barney as they embark on an epic quest to collect new words and complete the Encyclopedia of Everything.

In this top new word game and puzzle, you will Journey to exotic lands through over 100 cheesetastic levels of letter-linking fun. You can collect special characters on your travels to help you along the way, but watch out for those mousetraps and creeping vines. Play on your own or take on your friends to see who can get the highest score in the best game to ever ignite your word skills.

Heres a quick look at the features of the game:
• Link letters in any direction - up, down, diagonally, in fact, any way you want - even multiple directions!
• Three intrepid explorers on an epic journey
• Powerful boosters to help you crack challenging levels
• Bright and colorful graphics that will transport you to the far reaches of the mouse world
• Over 100 cheesetastic levels of letter-linking fun!
• Unlock boosters and unique characters with special abilities to help you along the way
• Play your way - long words or short words, race through levels or take your time, impress your friends or play by yourself, quick fun or leisurely indulgence - you choose.
• Easy and fun to play, challenging to master
• Easily sync the game between devices and unlock full game features when connected to the internet
• Leaderboards to follow your friends and competitors progress! Give lives, add friends and see your friends progress on the map in game.

AlphaBetty Saga is available for iOS and Android smartphones. While the game is free to play, it does contain in-app purchases to buy items such as extra moves or lives. Grab now the game for free on Google Play Store or download AlphaBetty Saga APK from the direct link given below and then install it on your Android phone and tablet.

Requires Android: 2.3+
Download File: 39MB (AlphaBetty Saga APK)

AlphaBetty Saga APK

Available link for download

Read more »

Allergy Seasons in Alaska

Allergy Seasons in Alaska


Internet  offers many allergy resources for US States. Examples are pollen.com providing allergy forecasts for US zip codes and American Academy of Allergy sources of allergy levels reported by certified counting stations. Weather.com features pollen maps too.  Neither of these sites, however, tells anything about Alaska and Hawaii.

Actually Alaskas Aerobiology is similar to Northern Europe, with some tree patterns resembling northern states of US. Pollination of poplar  - food for honey bees - starts in April - as in Michigan. Birch is very high in May - as in Russia and Scandinavia. Grass is active in June and July. A core pollen season of prophylactic and clinical urgency in Fairbanks and Anchorage is defined from May 10 to June 5.

You may want to visit Anchorage Daily news site  and Anchorage Pollen and Mold Reporting or Fairbanks area report to find today allergy information for Alaska, or check Dr. Andersons calendar below.  It is based on the observations made for six seasons: 1982-1987, from three sample locations in Fairbanks area, but represents a good prototype for other parts of Alaska.

 
This pollen calendar shows the range of possible atmospheric pollen concentrations for late April through July, assuming the weather is relatively warm, dry, and breezy.
pollen calendar
Reference: James H. Anderson, MLIS, PhD, Institute of Arctic Biology and BioSciences Library, University of Alaska Fairbanks



Available link for download

Read more »

Sunday, January 29, 2017

Anita Joseph shows off her boobs in new photos

Anita Joseph shows off her boobs in new photos



Niiiiice! One more below guys :D




Available link for download

Read more »

All Ears

All Ears


Hiya everyone! Im back from a short trip and my do I feel recharged inside and physically exhausted at the same time! When Im away I heard so many of you asking for this card in a more neutral mood. SO here it is everyone, the card in all occasion greetings. "thank you" and "best wishes". Kinda like 2 phrases in life you should have said the most, right? Feel free to download, click below, and dont forget to share your picture when youre using it.

download

Speaking of "phrases", maybe you have read it all over the net about JCPs slogan on girl t-shirt. No, Im not going to moan or rant all over the blog for it, but I would like to share my "if" quote now. I grew up with lots of boys around me, 1 big brother and 2 boy cousins who always hang around the house and I call brothers as well. IF my mom had bought me that JCP t shirt and I had worn it, I would not have lived by now. :) Share your thoughts about the t shirt here! Im in the mood for lending my ears!

Available link for download

Read more »

AMP v PTO Does Not Appear to Invalidate Very Many Gene Patent Method Claims

AMP v PTO Does Not Appear to Invalidate Very Many Gene Patent Method Claims


In this post, I explain why my recent analysis of 533 patents identified by Jensen and Murray as "gene patents" (described in a previous post) suggests the Federal Circuit’s recent decision in AMP v. PTO implicates the validity of very few gene patent method claims.

Background

As I pointed out in a blog post last December, the patent eligibility of Myriads claims to methods of detecting mutations in the BRCA gene by "analyzing" or "comparing" DNA sequences hinged entirely on the courts interpretation of the word "sequence" as it appears in the claims. In the field of molecular biology, the term "sequence" is routinely used not only to refer to the description of the chemical structure of a DNA molecule, but also to the actual DNA molecule as well.


For example, a scientist might say that "I determined the sequence of the BRCA gene." In this context, she is using the word sequence in reference to the abstract description of the order of nucleotides appearing in the gene. But the same scientist might also say that "I cloned the BRCA sequence into an expression vector," in which case she is using the term "sequence" to refer to the DNA molecule itself.

In the first example, "sequence" refers to abstract information describing a chemical structure, while in the second "sequence" is used to refer to a physical object, i.e., a specific DNA molecule. Molecular biologists are usually not bothered by the dual meaning of "sequence," because in practice the meaning of the term is understood based on the context in which it is used. However, it can lead to ambiguity, as seen in AMP v. PTO.

In AMP v. PTO, Myriad argued that as used in its claims the term "sequence" refers to an actual DNA molecule, and thus that analyzing or comparing "sequences of the BRCA gene" would involve physically manipulating and processing molecules in a manner that would render the claims patent eligible under Prometheus. I think it is clear that if the court had adopted this interpretation of "sequence" it would have upheld the validity of the claims. The ACLU plaintiffs never argued that a method claim that requires the analysis of physical DNA molecules would be patent ineligible.

Instead, as explained in a previous post, the ACLUs case was based on its argument that the term "sequence" in the claims refers to information, not to a physical molecule, and hence would cover the mental activity of analyzing or comparing genetic information. The court adopted the ACLUs interpretation of "sequence,” and ruled the claims patent ineligible for claiming nothing more than a mental step. This outcome was specifically dictated by the Federal Circuit’s earlier Prometheus decision, where it stated that a claim directed only to mental analysis of information is patent ineligible.

The Federal Circuit based its interpretation of “sequence” on its finding that Myriads patent specifications implicitly defined “sequence” broadly to cover pure information, as set forth in this excerpt from the case:

The patent specifications make clear that “sequence” does not exclusively specify a DNA molecule, but refers more broadly to the linear sequence of nucleotide bases of a DNA molecule. For example, Figure 10A–10H is described as showing the “genomic sequence of BRCA1.” ?473 patent col.5 l.66. Figure 10 does not show a physical DNA molecule; the figure lists a series of letters (Gs, As, Ts, and Cs) corresponding to the nucleotides guanine, adenine, thymine, and cytosine of a DNA molecule. Similarly, the patent specifications state that “[t]he nucleotide sequence for BRCA1 exon 4 is shown in SEQ ID NO: 11.” Id. col.53 ll.50–53. SEQ ID NO: 11 again lists a series of Gs, As, Ts, and Cs corresponding to the nucleotide sequence of BRCA1 exon 4.

Thus, Myriad’s claims might very well have been found patent eligible if the specification had defined the term "sequence" to refer only the DNA molecule itself. Alternatively, the claim probably would have been found patent eligible if it recited analyzing "DNA molecules" instead of analyzing sequences. If the claims could only be infringed by someone who physically analyzes the DNA molecule, it would certainly be patent eligible under the Federal Circuits interpretation of Bilski as set forth in Prometheus.

Claims that could be infringed by merely analyzing genetic data appear to be rare in Jensen and Murray dataset

In essence, Myriad’s method claims were patent ineligible because, as interpreted by the court, they could be infringed by analysis of genetic information. However, my research suggests that few if any of the gene patents identified by Jensen and Murray fall into this category. To the contrary, the vast majority of the claims in these patents would appear to be patent eligible.

Of the 533 patents I analyzed in my study, I only found 12 that included a claim reciting a method of analyzing a DNA sequence for a mutation or variation, and most if not all of those claims appear to require a physical manipulation of a patients DNA in order for there to be infringement.

In 8 of the 12 patents (6,395,482; 6,087,107; 6,458,541; 6,743,579; 5,830,649; 5,840,486; 5,955,265; and 6,410,226) the broadest claims specifically require obtaining a sample from a patients body, or analyzing for the genetic variation directly in a patients body.

For example, Claim 1 of US patent number 6,395,482 recites:

1. A method for determining susceptibility in a human subject to schizophrenia wherein the method comprises the steps of:

(a) removing a bodily sample from the subject, wherein the sample comprises a polynucleotide sequence of a PRODH gene;

(b) determining whether the PRODH gene of the bodily sample comprises a DNA sequence comprising a variation in SEQ ID NO:1 consisting of a T to C transition in the first position of codon 497, such that the presence of said variation in said PRODH gene is indicative of said subjects susceptibility to schizophrenia.
These eight claims would all appear to be patent eligible under AMP and Prometheus because they all involve physically manipulating a human sample obtained from patient.

The remaining four of the 12 patents (5,916,748; 6,630,304; 5,989,815; 6,432,644) are a little more ambiguous, and do not explicitly recite obtaining or analyzing a bodily sample. But arguably all of these claims do require physical manipulation of a sample, depending upon how a court interprets the claim, which will depend in part on how the claim terms were used in the patent specification

For example, Claim 1 of 6,432,644 recites:

1. A method for diagnosing the presence of a polymorphism in human KCNE1 (the coding region of which is bases 193-579 of SEQ ID NO:3) which causes long QT syndrome wherein said method is performed by means which identify the presence of said polymorphism, wherein said polymorphism is one which results in the presence of a KCNE1 polypeptide of SEQ ID NO:4 with an altered amino acid, said altered amino acid being selected from the group consisting of: a) a Leu at residue 74.
Note that this claim uses "means plus function" language, and would probably be interpreted to only cover means for identifying polymorphisms (a polymorphism is a genetic variation) that are described in the specification. If the only means for identifying polymorphisms described in the specification rely on physically analyzing DNA molecules, the claim would appear to be so-limited and thus patent eligible.

Similarly, Claim 1 of 6,630,304 recites:

1. A method of diagnosing a susceptibility to osteoporosis in an individual, comprising detecting a polymorphism in a human BMP2 gene of SEQ ID NO: 1, wherein the presence of a "T" at nucleotide position 11980 is indicative of a susceptibility to osteoporosis, compared with an individual having an "A" at nucleotide position 11980.
This claim refers to detecting a genetic variation in a "gene," as opposed to a "sequence" (the language used by Myriad). If a court were to interpret the claim limitation "detecting a polymorphism in the gene" as requiring actual analysis of a DNA molecule (which could depend upon how the term "gene" is using the specification), the claim would appear to be patent eligible. However, if the claim is interpreted to encompass detecting a polymorphism by analyzing genetic sequence data, it would appear to be patent ineligible.


Available link for download

Read more »

An Open Challenge to Advocates of Tax Cuts

An Open Challenge to Advocates of Tax Cuts


Ranting about the unfairness of taxes has become a national sport. Yet, tax cuts (without commensurate reductions in spending) are a prime contributor to the more than $12 trillion U.S. public debt that has been accumulated largely since 1981.

I challenge you to state how the U.S. federal government should generate an additional $1.5 trillion (give or take a few hundred billion) every year. Please be specific. Who should pay more in taxes? Who, if anyone, should pay less? It would be even better if you could find a politician who would make such a statement on the record.

It is easy to rant about the unfairness of ANY tax. Anti-tax advocates are making U.S. fiscal problems worse, not better. They add to a culture of fiscal irresponsibility in which we demand government services, but are unwilling to pay for them. Please do not misunderstand me. I am not opposed to the reduction or elimination of ANY government programs. But until such a time as politicians are willing to upset the portions of the electorate that benefit from government largesse by reducing their benefits, the responsible behavior is to pay for current government services rather than passing trillions of dollars of debt to our children, grandchildren, and future generations.

Keep ranting if it makes you feel better. But unless you support HIGHER taxes (on someone) or reduced government spending (on things YOU benefit from), then you are part of the problem, not the solution.

I await your plans for increasing federal government revenues or specific recommendations for $1.5 trillion (or more) in cuts to government services.

Best wishes ...

Available link for download

Read more »